Publikationen

Subnetz Genetische Schlaganfallforschung

Gispert S, Kubassek N, Hermans M, Hofer A, Raabe A, Ali Z, Tonn T, Trenkwalder C, Becker T, Steinmetz H, Auburger G. Evaluation of CYP46, IL1B, UCHL1 and ApoE alleles as genetic risk factors in Central European collectives of Parkinson’s disease and Intracranial Aneursym. (submitted).

Hofer A, Hermans M, Kubassek N, Sitzer M, Burtscher J, Knopp U, Schoch B, Wanke I, Hübner F, Raabe A, Steinmetz H, Auburger G. Lysyl oxidase as a candidate gene for intracranial aneurysms. Cerebrovasc Dis (in print).

2009

Gudbjartsson DF, Holm H, Gretarsdottir S, Thorleifsson G, Walters GB, Thorgeirsson G, Gulcher J, Mathiesen EB, Njølstad I, Nyrnes A, Wilsgaard T, Hald EM, Hveem K, Stoltenberg C, Kucera G, Stubblefield T, Carter S, Roden D, Ng MC, Baum L, So WY, Wong KS, Chan JC, Gieger C, Wichmann HE, Gschwendtner A, Dichgans M, Kuhlenbäumer G, Berger K, Ringelstein EB, Bevan S, Markus HS, Kostulas K, Hillert J, Sveinbjörnsdóttir S, Valdimarsson EM, Løchen ML, Ma RC, Darbar D, Kong A, Arnar DO, Thorsteinsdottir U, Stefansson K. A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. Nat Genet. 2009 Aug;41(8):876-8.
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2008

Gretarsdottir S, Thorleifsson G, Manolescu A, Styrkarsdottir U, Helgadottir A, Gschwendtner A, Kostulas K, Kuhlenbäumer G, Bevan S, Jonsdottir T, Bjarnason H, Saemundsdottir J, Palsson S, Arnar DO, Holm H, Thorgeirsson G, Valdimarsson EM, Sveinbjörnsdottir S, Gieger C, Berger K, Wichmann HE, Hillert J, Markus H, Gulcher JR, Ringelstein EB, Kong A, Dichgans M, Gudbjartsson DF, Thorsteinsdottir U, Stefansson K. Risk Variants for Atrial Fibrillation on Chromosome 4q25 Associate with Ischemic Stroke. Ann Neurol. 2008;64(4):402-9.
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Heidbreder AE, Ringelstein EB, Dittrich R, Nabavi D, Metze D, Kuhlenbäumer G. Assessment of skin extensibility and joint hypermobility in patients with spontaneous cervical artery dissection and Ehlers-Danlos syndrome. J Clin Neurosci. 2008 Jun;15(6):650-3.
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Uhlig P, Bruckner P, Dittrich R, Ringelstein EB, Kuhlenbäumer G, Hansen U. Aberrations of dermal connective tissue in patients with cervical artery dissection (sCAD). J Neurol. 2008 Mar;255(3):340-6.
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Völker W, Kuhlenbäumer G, Dittrich R, Appenzeller S, Grewe S, Maintz D, Heindel W, Grotemeyer KH, Ringelstein EB. Two sets of identical twins with cervical artery dissection concordant for temporal artery pathology. Neurology. 2008 Sep 23;71(13):1035-7.
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Völker W, Ringelstein EB, Dittrich R, Maintz D, Nassenstein I, Heindel W, Grewe S, Kuhlenbäumer G. Morphometric analysis of collagen fibrils in skin of patients with spontaneous cervical artery dissection. J Neurol Neurosurg Psychiatry. 2008 Sep;79(9):1007-12.
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2007

Berger K, Stögbauer F, Stoll M, Wellmann J, Huge A, Cheng S, Kessler C, John U, Assmann G, Ringelstein EB, Funke H. The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies. Hum Genet. 2007 Apr;121(2):169-78.
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Dittrich R, Heidbreder A, Rohsbach D, Schmalhorst J, Nassenstein I, Maintz D, Ringelstein EB, Nabavi DG, Kuhlenbäumer G. Connective tissue and vascular phenotype in patients with cervical artery dissection. Neurology. 2007 Jun 12;68(24):2120-4.
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Dittrich R, Nassenstein I, Bachmann R, Maintz D, Nabavi DG, Heindel W, Kuhlenbäumer G, Ringelstein EB. Polyarterial clustered recurrence of cervical artery dissection seems to be the rule. Neurology. 2007 Jul 10;69(2):180-6.
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Dittrich R, Rohsbach D, Heidbreder A, Heuschmann P, Nassenstein I, Bachmann R, Ringelstein EB, Kuhlenbaumer G, Nabavi DG; Mild mechanical traumas are possible risk factors for cervical artery dissection. Cerebrovasc Dis 2007; 23(4):275-81.
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Kuhlenbäumer G, Friedrichs F, Kis B, Berlit P, Maintz D, Nassenstein I, Nabavi D, Dittrich R, Stoll M, Ringelstein B. Association between single nucleotide polymorphisms in the lysyl oxidase-like 1 gene and spontaneous cervical artery dissection. Cerebrovasc Dis. 2007;24(4):343-8.
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2006

Berger K, Stogbauer F, Stoll M, Wellmann J, Huge A, Cheng S, Kessler C, John U, Assmann G, Ringelstein EB, Funke H; The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies. Hum Genet 2006; 121(2): 169-78.
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Kuhlenbäumer G, Berger K, Huge A, Lange E, Kessler C, John U, Funke H, Nabavi DG, Stogbauer F, Ringelstein EB, Stoll M. Evaluation of single nucleotide polymorphisms in the phosphodiesterase 4D gene (PDE4D) and their association with ischaemic stroke in a large German cohort. J Neurol Neurosurg Psychiatry. 2006; 77(4): 521-4.
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Kuhlenbäumer G, Berger K, Stoll M, Ringelstein EB; Komplexe Genetik des ischämischen Hirninfarktes. Nervenheilkunde 2006; 25 (11): 919-26.
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Kuhlenbäumer G, Konrad C, Kramer S, Kis B, Nabavi D, Dittrich R, Ringelstein EB. The collagen 1A2 polymorphism rs42524, which is associated with intracranial aneurysms, shows no association with spontaneous cervical artery dissection (sCAD). J Neurol Neurosurg Psychiatry. 2006; 77(1): 124-5.
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Wiest T, Hyrenbach S, Bambul P, Erker B, Pezzini A, Hausser I, Arnold M-L, Martin J-J, Engelter S, Lyrer P, Busse O, Brandt T, Grond-Ginsbach C; Genetic analysis of familial connective tissue alterations associated with cervical artery dissections suggests locus heterogeneity. Stroke 2006; 37: 1697-1702.
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2005

Konrad C, Langer C, Müller GA, Dziewas R, Stögbauer F, Junker R, Ringelstein EB, Kuhlenbäumer G. Protease-inhibitors in spontaneous cervical artery dissections. Stroke 2005; 36(1): 9-13.
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Volker W, Besselmann M, Dittrich R, Nabavi D, Konrad C, Dziewas R, Evers S, Grewe S, Kramer SC, Bachmann R, Stogbauer F, Ringelstein EB, Kuhlenbaumer G. Generalized arteriopathy in patients with cervical artery dissection. Neurology. 2005; 64(9): 1508-13. Erratum in: Neurology. 2005; 64 (12): 2147.
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2004

Grond-Ginsbach C, Engelter S, Werner I, Hausser I, Müller U, Brandt T, Lyrer P. Alpha-1-antitrypsin deficiency alleles are not associated with cervical artery dissections. Neurology 2004; 62(7): 1190-2.
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Hausser I, Müller U, Engelter S, Lyrer P, Pezzini A, Padovani A, Moormann B, Busse O, Weber R, Brandt T, Grond-Ginsbach C. Different types of connective tissue alterations associated with cervical artery dissections. Acta Neuropathol (Berl) 2004; 107(6): 509-14.
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Konrad C, Müller GA, Langer C, Kuhlenbäumer G, Berger K, Dziewas R, Stögbauer F, Ringelstein EB, Junker R. Plasma Homocysteine, MTHFR C677T, CBS 844ins68bp and MTHFD1 G1958A Polymorphisms in Spontaneous Cervical Artery Dissections. J Neurol 2004; 251(10): 1242-8.
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Kuhlenbäumer G, Müller U, Besselmann M, Rauterberg J, Robenek H, Hünermund G, Brandt T, Ringelstein EB, Stögbauer F. Neither collagen 8A1 nor 8A2 mutations play a major role in cervical artery dissection: a mutation analysis and linkage study. J Neurol 2004; 251(3): 357-9.
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Kuhlenbäumer G, Ringelstein EB, Stogbauer F. Spontaneous dissection of brain providing neck artery. Fortschr Neurol Psychiatr. 2004; 72(5): 282-91.
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Wagner S, Kluge B, Koziol J, Grau A, Grond-Ginsbach C. MMP-9 polymorphisms are not associated with spontaneous cervical artery dissection. Stroke 2004; 35(3): 62-4.
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Wiest T, Werner I, Brandt T, Grond-Ginsbach C. Interleukin 6 (IL-6) promoter variants in patients with spontaneous cervical artery dissections. Cerebrovasc Dis 2004; 17(4): 347-8.
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2003

Dziewas R, Konrad C, Dräger B, Evers S, Besselmann M, Lüdemann P, Kuhlenbäumer G, Stögbauer F, Ringelstein EB. Cervical artery dissection – clinical features, risk factors, therapy and outcome in 126 patients. J Neurol 2003; 250(10): 1179-84.
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Hofer A, Hermans M, Kubassek N, Sitzer M, Funke H, Stögbauer F, Ivaskevicius V, Oldenburg J, Burtscher J, Knopp U, Schoch B, Wanke I, Hubner F, Deinsberger W, Meyer B, Boecher-Schwarz H, Poewe W, Raabe A, Steinmetz H, Auburger G. Elastin polymorphism haplotype and intracranial aneurysms are not associated in Central Europe. Stroke 2003; 34(5): 1207-11.
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Morcher M, Hausser I, Brandt T, Grond-Ginsbach C. Heterozygous carriers of Pseudoxanthoma elasticum were not found among patients with cervical artery dissections. J Neurol 2003; 250: 983-6.
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Pezzini A, Hausser I, Brandt T, Padovani A, Grond-Ginsbach C. Internal carotid artery dissection after French horn playing. Spontaneous or traumatic event? J Neurol 2003; 250: 1004-5.
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Subnetz Experimentelle Schlaganfallforschung

Bührle C, Blunk J, Sprenger C, Wiedermann D, Küstermann E, Hoehn M. Superparamagnetic iron oxide nanoparticles (USPIOs) as bifunctional tools for in vivo research using high resolution MRI, histochemistry and immunohistochemistry on cells grafted into the vertebrate brain. Journal of Molecular Imaging (submitted)

Kreischer S, Stehling F, Bröker M, Haupt K, Volbracht L, Wiegand F, Diener HC, Busch E. Intracerebral hemorrhages and the plasminogen-system after rt-PA treatment of thromboembolic stroke in the rat. Stroke (submitted)

Küstermann E, Wiedermann D, Bührle C, Arnold H, Föcking M, Trapp T, Hoehn M. A systematic investigation on an efficient method to label stem cells for longitudinal in vivo NMR studies. (submitted)

Niessen F, T. Hilger T, Hoehn M, Hossmann KA. Relationship between stroke severity and outcome of thrombolytic treatment. (submitted)

Stehling F, Kreischer S, Bröker M, Haupt K, Volbracht L, Diener HC, Busch E. Effect of rt-PA treatment of thromboembolic stroke in the rat on coagulation parameters and the serine/serpine-system. J Cereb Blood Flow Metab (submitted)

2008

Petzold GC, Haack S, von Bohlen Und Halbach O, Priller J, Lehmann TN, Heinemann U, Dirnagl U, Dreier JP. Nitric oxide modulates spreading depolarization threshold in the human and rodent cortex. Stroke. 2008 Apr;39(4):1292-9.
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2007

Endres M, Piriz J, Gertz K, Harms C, Meisel A, Kronenberg G, Torres-Aleman I. Serum insulin-like growth factor I and ischemic brain injury. Brain Res. 2007 Dec 14;1185:328-35.
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Harms C, Albrecht K, Harms U, Seidel K, Hauck L, Baldinger T, Hübner D, Kronenberg G, An J, Ruscher K, Meisel A, Dirnagl U, von Harsdorf R, Endres M, Hörtnagl H. Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21(Waf1/Cip1) as a novel mechanism of neuroprotection by glucocorticoids. J Neurosci. 2007 Apr 25;27(17):4562-71.
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Hauck L, Harms C, Grothe D, An J, Gertz K, Kronenberg G, Dietz R, Endres M, von Harsdorf R. Critical role for FoxO3a-dependent regulation of p21CIP1/WAF1 in response to statin signaling in cardiac myocytes. Circ Res. 2007 Jan 5;100(1):50-60.
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2006

Endres M; Statins: potential new indications in inflammatory conditions. Atherosclerosis Suppl 2006; 7: 31-35.
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2005

Maurer MH, Feldmann RE Jr, Fütterer CD, Butlin J, Kuschinsky W. Comprehensive proteome expression profiling of undifferentiated vs. differentiated neural stem cells from adult rat hippocampus. Neurochem Res. 2005; 30(1):159.
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2004

Hamann GF, Burggraf D, Martens HK, Liebetrau M, Jager G, Wunderlich N, DeGeorgia M, Krieger DW. Mild to moderate hypothermia prevents micro vascular basal lamina antigen loss in experimental focal cerebral ischemia. Stroke 2004; 35(3): 764-9.
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2003

Burggraf D, Martens KH, Jäger G, Hamann GF. Recombinant human tissue plasminogen activator protects the basal lamina in experimental focal cerebral ischemia. Thromb Haemost 2003; 89: 1072-80.
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Busch E, Diener HC. Schlaganfallverbund Essen. Notfall & Rettungsmedizin 2003; 6: 292-8.

Busch E, Diener HC. Schlaganfallversorgung: Mit Netzwerken auf innovativen Wegen. Deutsches Ärzteblatt 2003; 40: 2567-9.

Erdö F, Bührle C, Blunk J, Hoehn M, Xia Y, Fleischmann B, Föcking B, Küstermann E, Kolossov E, Hescheler J, Hossmann KA, Trapp T. Host-dependent tumorigenesis of embryonic stem cell transplantation in experimental stroke. J Cereb Blood Flow Metab 2003; 23: 780-5.
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Hamann GF, Schroeck H, Burggraf D, Wunderlich N, Liebetrau M, Kuschinsky W. Microvascular basal lamina damage after embolic stroke in the rat: relation to cerebral blood flow. J Cereb Blood Flow Metab 2003; 23: 1293-7.
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Hamann GF. Unriddling the role of matrix metalloproteinases in human cerebral stroke. Stroke 2003; 34: 40-6.
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Hossmann KA. Naturwissenschaftlich-medizinische Bemerkungen zu den Aspekten der Hochrangigkeit und der Alternativlosigkeit bei der Forschung mit embryonalen Stammzellen. Jahrbuch für Wissenschaft und Ethik 2003; 8: 295-303.

Hossmann KA. Tumorrisiko embryonaler Stammzellen. Deutsches Ärzteblatt 2003; 100: 2136.

Maurer MH, Feldmann RE Jr, Fütterer CD, Kuschinsky W. The proteome of neural stem cells from adult rat hippocampus. Proteome Sci 2003; 1;4
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Maurer MH, Tripps WKC, Feldmann Jr RE, Kuschinsky W. Expression of vascular endothelial growth factor and its receptors in rat neural stem cells. Neurosci Lett 2003; 344: 165-8.
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Muellner A, Benz M, Kloss CU, Mautes A, Burggraf D, Hamann GF. Microvascular basal lamina antigen loss after traumatic brain injury in the rat. J Neurotrauma 2003; 20: 745-54.
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Niessen F, Hilger T, Hoehn M, Hossmann KA. Differences in clot preparation determine outcome of rt-PA treatment in experimental thromboembolic stroke. Stroke 2003; 34: 2019-24.
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Vosko MR, Busch E, Burggraf D, Bueltemeier G, Hamann GF. Microvascular basal lamina damage in thromboembolic stroke in a rat model.Neurosci Let 2003; 353: 217-20.
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Vosko MR, Röther J, Friedl B, Bültemeier G, Kloss CU, Hamann GF. Microvascular damage following experimental sinus-vein thrombosis in rats. Acta Neuropatholog 2003; 106: 501-5.
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2002

Neumann-Haefelin C, Brinker G, Uhlenkuken U, Pillekamp F, Hossmann KA, Hoehn M. Prediction of Hemorrhagic Transformation After Thrombolytic Therapy of Clot Embolism. Stroke 2002; 33: 1392-8.
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Niessen F, Hilger T, Hoehn M, Hossmann KA. Thrombolytic treatment of clot embolism in rat: comparison of intra-arterial and intravenous application of recombinant tissue plasminogen activator. Stroke 2002; 33(12): 2999-3005.
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Subnetz Bildgebende Verfahren beim Schlaganfall

2010

Thomalla G, Hartmann F, Juettler E, Singer OC, Lehnhardt FG, Köhrmann M, Kersten JF, Krützelmann A, Humpich MC, Sobesky J, Gerloff C, Villringer A, Fiehler J, Neumann-Haefelin T, Schellinger PD, Röther J. Prediction of malignant middle cerebral artery infarction by magnetic resonance imaging within 6 hours of symptom onset: A prospective multicenter observational study. Ann Neurol. 2010 Oct;68(4):435-45.
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2009

Thomalla G., Audebert H.J., Berger K., Fiebach J.B., Fiehler J., Kaps M., Neumann-Haefelin T., Schellinger P.D., Siebler M., Sobesky J., Villringer A., Witte O.W., Röther J. Bildgebung beim Schlaganfall - eine Übersicht und Empfehlungen des Kompetenznetzes Schlaganfall. Akt Neurol 2009; 36: 354-367.
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2008

Brunecker P, Endres M, Nolte CH, Schultze J, Wegener S, Jungehülsing GJ, Müller B, Kerskens CM, Fiebach JB, Villringer A, Steinbrink J. Evaluation of an AIF correction algorithm for dynamic susceptibility contrast-enhanced perfusion MRI. Magn Reson Med. 2008 Jul;60(1):102-10.
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Nolte CH, Gruss J, Steinbrink J, Jungehulsing GJ, Brunecker P, Hopt AM, Schreiber SJ. Ultrasound Perfusion Imaging of Small Stroke Involving the Thalamus. Ultraschall Med. 2008 Jun 5.

Orakcioglu B, Becker K, Sakowitz OW, Herweh C, Köhrmann M, Huttner HB, Steiner T, Unterberg A, Schellinger PD. MRI of the perihemorrhagic zone in a rat ICH model: effect of hematoma evacuation. Neurocrit Care. 2008;8(3):448-55.
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Wittsack HJ, Wohlschläger AM, Ritzl EK, Kleiser R, Cohnen M, Seitz RJ, Mödder U. CT-perfusion imaging of the human brain: advanced deconvolution analysis using circulant singular value decomposition. Comput Med Imaging Graph. 2008 Jan;32(1):67-77.
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2007

Brunecker P, Schultze J, Nolte CH, Jungehülsing GJ, Endres M, Villringer A, Steinbrink J. Correcting saturation effects of the arterial input function in dynamic susceptibility contrast-enhanced MRI: a Monte Carlo simulation. Magn Reson Imaging, 2007; VOL 25(9):1300-11.
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Leithner C, Gertz K, Schröck H, Priller J, Prass K, Steinbrink J, Villringer A, Endres M, Lindauer U, Dirnagl U, Royl G. A flow sensitive alternating inversion recovery (FAIR)-MRI protocol to measure hemispheric cerebral blood flow in a mouse stroke model. Exp Neurol. 2008 Mar;210(1):118-27. Epub 2007 Oct 18.
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Thomalla G, Kohrmann M, Rother J, Schellinger PD. Effektive Schlaganfalltherapie jenseits der Zulassungsbeschränkungen: intravenöse Thrombolyse im erweiterten Zeitfenster (> 3 h) und bei alten Patienten (> 80 J.) [Effective Acute Stroke Treatment Beyond Approval Limitations: Intravenous Thrombolysis within an Extended Time Window (3 - 6 h) and in Old Patients (Aged 80 or Older).] Fortschr Neurol Psychiatr. 2007;75:343-50.
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Thomalla G, Sobesky J, Köhrmann M, Fiebach JB, Fiehler J, Zaro Weber O, Kruetzelmann A, Kucinski T, Rosenkranz M, Röther J, Schellinger PD. Two tales: hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is related to severity and duration of ischemia: MRI study of acute stroke patients treated with intravenous tissue plasminogen activator within 6 hours.Stroke 2007;38(2):313-8.
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2006

Bütefisch CM, Kleiser R, Seitz RJ. Post-lesional cerebral reorganisation: evidence from functional neuroimaging and transcranial magnetic stimulation. J Physiol 2006; 99(4-6): 437-54.
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Huttner HB, Hartmann M, Kohrmann M, Neher M, Stippich C, Hahnel S, Kress B. Repeated digital substraction angiography after perimesencephalic subarachnoid hemorrhage? J Neuroradiol 2006; 33(2): 87-9.
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Huttner HB, Steiner T, Hartmann M, Kohrmann M, Jüttler E, Mueller S, Wikner J, Meyding-Lamade U, Schramm P, Schwab S, Schellinger PD. Comparison of ABC/2 estimation technique to computer-assisted planimetric analysis in warfarin-related intracerebral parenchymal hemorrhage. Stroke 2006; 37(2): 404-8.
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Jungehülsing GJ, Nolte CH, Brunecker P, Villringer A; MR-Bildgebung beim akuten Schlaganfall - Ergebnisse aus dem ImagingNet im Kompetenznetz Schlaganfall. Nervenheilkunde 2006; 25 (11): 927-32.
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Jungehülsing GJ, Rossnagel K, Nolte CH, Müller-Nordhorn J, Roll S, Klein M, Wegscheider K, Einhäupl KM, Willich SN, Villringer A; Emergency department delays in acute stroke - analysis of time between ED arrival and imaging. Eur J Neurol 2006; 13(3): 225-32.
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Jüttler E, Fiebach JB, Schellinger PD; Diagnostic imaging for acute ischemic stroke management. Expert Rev Med Devices 2006; 3(1): 113-26.
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Kohrmann M, Jüttler E, Fiebach JB, Huttner HB, Siebert S, Schwark C, Ringleb PA, Schellinger PD, Hacke W; MRI versus CT-based thrombolysis treatment within and beyond the 3 h time window after stroke onset: a cohort study. Lancet Neurol 2006; 5: 661-7.
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Masdeu JC, Irimia P, Asenbaum S, Bogousslavsky J, Brainin M, Chabriat H, Herholz K, Markus HS, Martinez-Vila E, Niederkorn K, Schellinger PD, Seitz RJ; EFNS guideline on neuroimaging in acute stroke. Report of an EFNS task force. Eur J Neurol 2006; 13: 1271-83.
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Surikova I, Meisel S, Wittsack HJ, Siebler M, Seitz RJ; Significance of the perfusion-diffusion mismatch in chronic cerebral ischemia. J Magn Reson Imaging 2006; 24: 771-8.
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Thomalla G, Schwark C, Sobesky J, Bluhmki E, Fiebach JB, Fiehler J, Zaro-Weber O, Kucinski T, Juettler E, Ringleb PA, Zeumer H, Weiller C, Hacke W, Schellinger PD, Röther J; for the MRI in Acute Stroke Study Group of the German Competence Network Stroke. Outcome and Symptomatic Bleeding Complications of IV-Thrombolysis Within 6 Hours in MRI Selected Stroke Patients. Comparison of a German Multicenter Study Compared with the Pooled Data of ATLANTIS, ECASS and NINDS tPA Trials. Stroke 2006; 37(3): 852-8.
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Wintermark M, Fiebach J; Iodinated and gadolinium contrast media in computed tomography (CT) and magnetic resonance (MR) stroke imaging. Curr Med Chem 2006; 13(22): 2717-23.
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2005

Fiehler J, Remmele C, Kucinski T, Rosenkranz M, Thomalla G, Weiller C, Zeumer H, Rother J. Reperfusion after Severe Local Perfusion Deficit Precedes Hemorrhagic Transformation: An MRI Study in Acute Stroke Patients. Cerebrovasc Dis. 2005; 19(2): 117-24.
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Kraemer N, Thomalla G, Soennichsen J, Fiehler J, Knab R, Kucinski T, Zeumer H, Rother J. Magnetic Resonance Imaging and Clinical Patterns of Patients with 'Spectacular Shrinking Deficit' after Acute Middle Cerebral Artery Stroke. Cerebrovasc Dis. 2005; 20(5): 285-90.
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Kucinski T, Naumann D, Knab R, Schoder V, Wegener S, Fiehler J, Majumder A, Rother J, Zeumer H. Tissue at Risk Is Overestimated in Perfusion-Weighted Imaging: MR Imaging in Acute Stroke Patients without Vessel Recanalization. AJNR Am J Neuroradiol. 2005; 26: 815-9.
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Taskin B, Jungehulsing GJ, Ruben J, Brunecker P, Krause T, Blankenburg F, Villringer A. Preserved Responsiveness of Secondary Somatosensory Cortex in Patients with Thalamic Stroke. Cerebral Cortex 2005; doi:10.1093/cercor/bhj080.
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Thomalla G, Schwark C, Sobesky J, Bluhmki E, Fiebach JB, Fiehler J, Zaro-Weber O, Kucinski T, Jüttler E, Ringleb P, Schellinger P; Rother J. Das Outcome nach Thrombolyse im 6h Zeitfenster bei Patienten mit DWI/PWI Mismatch ist unabhängig von der Zeit und besser als bei unselektiertem Patienten. Akt Neurol. 2005; VOL: 32(S4): 141.
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Wegener S, Weber R, Ramos-Cabrer P, Uhlenkueken U, Wie-dermann D, Kandal K, Villringer A, Hoehn M. Subcortical lesions after transient thread occlusion in the rat: T2-weighted magnetic resonance imaging findings without corresponding sensorimotor deficits. J Magn Reson Imaging 2005; 21 (4): 340-6.
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2004

Fiebach JB, Schellinger PD, Gass A, Kucinski T, Siebler M, Villringer A, Ölkers P, Hirsch JG, Heiland S, Wilde P, Jansen O, Röther J, Hacke W, Sartor K; Kompetenznetzwerk Schlaganfall. Stroke MRI is accurate in hyperacute intracerebral hemorrhage. A multicenter study on the validity of stroke imaging. Stroke 2004; 35(2): 502-6.
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Fiebach JB, Schellinger PD, Geletneky K, Wilde P, Meyer M, Hacke W, Sartor K. MRI in acute subarachnoid haemorrhage; findings with a standardised stroke protocol. Neuroradiology 2004; 46: 44-8.
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Fiehler J, Knudsen K, Kucinski T, Kidwell CS, Alger JR, Thomalla G, Eckert B, Wittkugel O, Weiller C, Zeumer H, Rother J. Predictors of apparent diffusion coefficient normalization in stroke patients. Stroke 2004; 35: 514-9.
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Gass A, Ay H, Szabo K, Koroshetz WJ. Diffusion-weighted MRI for the "small stuff": the details of acute cerebral ischaemia. Lancet Neurol 2004; 3: 39-45.
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Kucinski T, Majumder A, Knab R, Naumann D, Fiehler J, Vaterlein O, Eckert B, Rother J, Zeumer H. Cerebral perfusion impairment correlates with the decrease of CT density in acute ischaemic stroke. Neuroradiology. 2004; 46: 716-22.
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Lie C, Hirsch JG, Rossmanith C, Hennerici MG, Gass A. Clinicotopographical correlation of corticospinal tract stroke: a color-coded diffusion tensor imaging study. Stroke 2004; 35: 86-92.
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Ritzl A, Meisel S, Wittsack H-J, Fink GR, Siebler M, Mödder U, Seitz RJ. Development of Brain Infarct Volume as assessed by Magnetic Resonance Imaging: Follow-up of DWI-lesions. J Magn Reson Imaging 2004; 20(2): 201-7.
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Schellinger PD. MRI-guided therapy in acute stroke. Expert Rev Cardiovasc Ther 2004; 1(4): 569-80.
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Singer OC, du Mesnil de Rochemont R, Foerch C, Stengel A, Sitzer M, Lanfermann H, Neumann-Haefelin T. Early functional recovery and the fate of the diffusion/perfusion mismatch in patients with proximal middle cerebral artery occlusion. Cerebrovasc Dis 2004; 17(1): 13-20.
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Straub S, Junghans U, Jovanovic V, Wittsack HJ, Seitz RJ, Siebler M. Systemic thrombolysis with recombinant tissue plasminogen activator and tirofiban in acute middle cerebral artery occlusion. Stroke 2004; 35: 705-9.
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Wegener S, Gottschalk B, Jovanovic V, Knab R, Fiebach JB, Schellinger PD, Kucinski T, Jungehülsing GJ, Peter Brunecker P, Müller B, Banasik A, Amberger N, Wernecke KD, Siebler M, Röther J, Villringer A, Weih M. TIAs before ischemic stroke: preconditioning the human brain? A multicenter MRI-study. Stroke 2004; 35(3): 616-21.
externer Link

2003

Doege CA, Kerskens CM, Romero BI, Brunecker P, Jungehülsing GJ, Von Pannwitz W, Müller B, Villringer A. Assessment of diffusion and perfusion deficits in patients with small subcortical ischemia. Am J Neuroradiol 2003; 24: 1355-63.
externer Link

Fiebach JB, Schellinger PD. [Modern magnetic resonance techniques in stroke] Radiologe 2003; 43(3): 251-63; quiz 263-4.
externer Link

Huber R, Muller BT, Seitz RJ, Siebler M, Modder U, Sandmann W. Carotid surgery in acute symptomatic patients. Eur J Vasc Endovasc Surg 2003 ; 25: 60-7.
externer Link

Junghans U, Siebler M. Cerebral microembolism is blocked by tirofiban, a selective nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist. Circulation 2003; 107: 2717-21.
externer Link

Krep H, Bottiger BW, Bock C, Kerskens CM, Radermacher B, Fischer M, Hoehn M, Hossmann KA. Time course of circulatory and metabolic recovery of cat brain after cardiac arrest assessed by perfusion- and diffusion-weighted imaging and MR-spectroscopy. Resuscitation 2003; 58: 337-48.
externer Link

Kucinski T, Koch C, Eckert B, Becker V, Kromer H, Heesen C, Grzyska U, Freitag HJ, Rother J, Zeumer H. Collateral circulation is an independent radiological predictor of outcome after thrombolysis in acute ischaemic stroke. Neuroradiology 2003; 45: 11-8.
externer Link

Neumann-Haefelin T, Du Mesnil De Rochemont R, Fiebach JB, Gass A, Nolte C, Kucinski T, Röther J, Siebler M, Singer O, Szabo K, Villringer A, Schellinger PD. Effect of incomplete (spontaneous and post-thrombolytic) recanalization following middle cerebral artery occlusion: a magnetic resonance imaging study. Stroke 2003; 35(1): 109-14.
externer Link

Rother J. Imaging-guided extension of the time window: ready for application in experienced stroke centers? Stroke 2003; 34: 575-83.
externer Link

Sartor K, Hartmann M, Fiebach J, Harting I, Wilhelm T, Heiland S. [Normal and abnormal water diffusion in the brain] Rofo Fortschr Geb Röntgenstr Neuen Bildgeb Verfahr 2003; 175: 1317-29.
externer Link

Saur D, Kucinski T, Grzyska U, Eckert B, Eggers C, Niesen W, Schoder V, Zeumer H, Weiller C, Rother J. Sensitivity and interrater agreement of CT and diffusion-weighted MR imaging in hyperacute stroke. Am J Neuroradiol 2003; 24: 878-85.
externer Link

Schellinger PD, Fiebach JB, Hacke W. Imaging-based decision making in thrombolytic therapy for ischemic stroke: present status (2003). Stroke 2003; 34: 575-83.
externer Link

Schellinger PD, Fiebach JB, Hoffmann K, Becker K, Orakcioglu B, Kollmar R, Juttler E, Schramm P, Schwab S, Sartor K, Hacke W. Stroke MRI in intracerebral hemorrhage: is there a perihemorrhagic penumbra? Stroke 2003; 34(7): 1674-9.
externer Link

Schellinger PD, Fiebach JB. [Diagnostics and treatment of acute stroke] Fortschr Neurol Psychiatr 2003; 71: 423-38; quiz 439-40.
externer Link

Seitz RJ, Hamzavi M, Junghans U, Ringleb PA, Schranz C, Siebler M. Thrombolysis with recombinant tissue plasminogen activator and tirofiban in stroke: preliminary observations. Stroke 2003; 34: 1932-5.
externer Link

Singer OC, Du Mesnil De Rochemont R, Foerch C, Stengel A, Lanfermann H, Sitzer M, Neumann-Haefelin T. Relation between relative cerebral blood flow, relative cerebral blood volume, and mean transit time in patients with acute ischemic stroke determined by perfusion-weighted MRI. J Cereb Blood Flow Metab 2003; 23(5): 605-11.
externer Link

Thomalla GJ, Kucinski T, Schoder V, Fiehler J, Knab R, Zeumer H, Weiller C, Röther J. Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging. Stroke 2003; 34: 1892-9.
externer Link

2002

Fiebach JB, Schellinger PD, Jansen O, Meyer M, Wilde P, Bender J, Schramm P, Jüttler E, Oehler J, Hartmann M, Hähnel S, Knauth M, Hacke W, Sartor K. CT and diffusion-weighted MR imaging (DWI) in randomized order: DWI results in higher accuracy and lower interrater variability in the diagnosis of hyperacute ischemic stroke. Stroke 2002; 33: 2206-10.
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Fiehler J, Fiebach JB, Gass A, Hoehn M, Kucinski T, Neumann-Haefelin T, Schellinger PD, Siebler M, Villringer A, Rother J. Diffusion-weighted imaging in acute stroke-a tool of uncertain value? Cerebrovasc Dis 2002; 14(3-4): 187-96.
externer Link

Fiehler J, Foth M, Kucinski T, Knab R, von Bezold M, Weiller C, Zeumer H, Rother J. Severe ADC decreases do not predict irreversible tissue damage in humans. Stroke 2002; 33(1): 79-86.
externer Link

Fiehler J, von Bezold M, Kucinski T, Knab R, Eckert B, Wittkugel O, Zeumer H, Rother J. Cerebral blood flow predicts lesion growth in acute stroke patients. Stroke 2002; 33(10): 2421-5.
externer Link

Hilger T, Niessen F, Diedenhofen M, Hossmann KA, Hoehn M. Magnetic resonance angiography of thromboembolic stroke in rats: indicator of recanalization probability and tissue survival after recombinant tissue plasminogen activator treatment. J Cereb Blood Flow Metab 2002; 22: 652-62.
externer Link

Hoehn M, Kustermann E, Blunk J, Wiedermann D, Trapp T, Wecker S, Focking M, Arnold H, Hescheler J, Fleischmann BK, Schwindt W, Buhrle C. Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci U S A 2002; 99: 16267-72.
externer Link

Junghans U, Seitz RJ, Ritzl A, Wittsack HJ, Fink GR, Freund HJ, Siebler M. Ischemic brain tissue salvaged from infarction by the GP IIb/IIIa platelet antagonist tirofiban. Neurology 2002; 58:474-476.
externer Link

Neumann-Haefelin C, Brinker G, Uhlenkuken U, Pillekamp F, Hossmann KA, Hoehn M. Prediction of hemorrhagic transformation after thrombolytic therapy of clot embolism: an MRI investigation in rat brain. Stroke 2002; 33:1392-8.
externer Link

Rother J, Schellinger PD, Gass A, Siebler M, Villringer A, Fiebach JB, Fiehler J, Jansen O, Kucinski T, Schoder V, Szabo K, Jungehülsing GJ, Hennerici M, Zeumer H, Sartor K, Weiller C, Hacke W; Kompetenznetzwerk Schlaganfall Study Group. Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 hours. Stroke 2002; 33: 2438-45.
externer Link

Szabo K, Gass A, Hennerici MG. Diffusion and perfusion MRI for the assessment of carotid atherosclerosis. Neuroimaging Clin N Am 2002; 12(3): 381-90.
externer Link

Szabo K, Gass A, Rossmanith C, Hirsch JG, Hennerici MG. Diffusion- and perfusion-weighted MRI demonstrates synergistic lesions in acute ischemic Foix-Chavany-Marie syndrome. J Neurol 2002; 249(12): 1735-7.
externer Link

van Dorsten FA, Olah L, Schwindt W, Grune M, Uhlenkuken U, Pillekamp F, Hossmann KA, Hoehn M. Dynamic changes of ADC, perfusion, and NMR relaxation parameters in transient focal ischemia of rat brain. Magn Reson Med 2002; 47: 97-104.
externer Link

Wittsack HJ, Ritzl A, Fink GR, Wenserski F, Siebler M, Seitz RJ, Modder U, Freund H-J. MR Imaging in Acute Stroke: Diffusion-weighted and Perfusion Imaging Parameters for Predicting Infarct Size. Radiology 2002; 222: 397-403.
externer Link

Subnetz Telemedizin

2009

Audebert H.J., Berger K., Boy S., Einhäupl K.M., Endres M., Gahn G., Handschu R., Kaps M., Kuschinsky W., Lichy C., Röther J., Schenkel J., Scibor M., Schleyer A., Siebler M., Witte O.W., Ziegler V., Villringer A. Telemedizin in der akuten Schlaganfallversorgung - Review und Empfehlungen des Kompetenznetzes Schlaganfall. Akt Neurol 2009; 36: 82-90.
externer Link

2008

Audebert HJ, Boy S, Jankovits R, Pilz P, Klucken J, Fehm NP, Schenkel J. Is mobile teleconsulting equivalent to hospital-based telestroke services? Stroke. 2008 Dec;39(12):3427-30.
externer Link

Audebert HJ, Schenk B, Tietz V, Schenkel J, Heuschmann PU. Initiation of oral anticoagulation after acute ischaemic stroke or transient ischaemic attack: timing and complications of overlapping heparin or conventional treatment. Cerebrovasc Dis. 2008;26(2):171-7.
externer Link

Audebert HJ, Schultes K, Tietz V, Heuschmann PU, Bogdahn U, Haberl RL, Schenkel J; Writing Committee for the Telemedical Project for Integrative Stroke Care (TEMPiS). Long-Term Effects of Specialized Stroke Care With Telemedicine Support in Community Hospitals on Behalf of the Telemedical Project for Integrative Stroke Care (TEMPiS). Stroke. 2008 Nov 20. [Epub ahead of print]
externer Link

Vatankhah B, Schenkel J, Fürst A, Haberl RL, Audebert HJ. Telemedically provided stroke expertise beyond normal working hours. The Telemedical Project for Integrative Stroke Care. Cerebrovasc Dis. 2008;25(4):332-7.
externer Link

2007

Audebert HJ, Haberl RL, Hacke W, Handschu R, Schenkel J, Scibor M, Schleyer AM, Siebler M, Vatankhah B, Wiborg A, Widder B. Telemedizin in der akuten Schlaganfallversorgung - Eine Standortbestimmung. Deutsche medizinische Wochenschrift 2007;132:431-6.
externer Link

Müller R, Pfefferkorn T, Vatankhah B, Mayer TE, Schenkel J, Dichgans M, Sander D, Audebert HJ. Admission facility is associated with outcome of basilar artery occlusion. Stroke. 2007 Apr;38(4):1380-3.
externer Link

Schleyer AM, Ruf D, Nowak B, Derr F, Widder B. Shortening „door-to-telemedicine” time in a rural telemedicine network through wireless teleconsultation – videobased telemedicine information system (VITIS). Cerebrovasc Dis 2007;23(suppl 2):57–80.

2006

Audebert H; Telestroke: effective networking. Lancet Neurol. 2006; 5: 279-82.
externer Link

Audebert HJ, Kukla C, Vatankhah B et al. Comparison of tissue plasminogen activator administration management between Telestroke Network hospitals and academic stroke centers: the Telemedical Pilot Project for Integrative Stroke Care in Bavaria/Germany. Stroke 2006; 37: 1822-27.
externer Link

Audebert HJ, Schenkel J Heuschmann PU et al. Effects of the implementation of a telemedical stroke network: the Telemedic Pilot Project for Integrative Stroke Care (TEMPiS) in Bavaria, Germany. Lancet Neurol. 2006; 5: 742-48.
externer Link

Müller H, Nimmrichter B, Schenkel J, Haberl RL, Audebert HJ; Verbesserung der Schlaganfall-Behandlung in einem regionalen Versorgungskrankenhaus; Prozessqualität vor und nach Einbindung in ein telemedizinisch unterstütztes Schlaganfall-Netzwerk. DMW 2006; 131: 1309-14.
externer Link

2005

Ickenstein GW, Horn M, Schenkel J, Vatankhah B, Bogdahn , Haberl R, Audebert HJ. The use of telemedicine in combination with a new stroke-code-box sig-nificantly increases tPA-utilization in rural communities. Neurocrit Care 2005; 3(1): 27-32.
externer Link

2004

Audebert HJ, Wimmer ML, Schenkel J, Ulm K, Kolominsky-Rabas PL, Bogdahn U, Horn M, Haberl RL. Telemedical stroke care networks – design and efficiency analysis of a pilot project in southeast Bavaria. Nervenarzt 2004; 75(2): 161-5.
externer Link

2003

Handschu R, Littmann R, Reulbach U, Gaul C, Heckmann JG, Neundorfer B, Scibor M. Telemedicine in emergency evaluation of acute stroke: interrater agreement in remote video examination with a novel multimedia system. Stroke 2003; 34: 2842-6.
externer Link

Wiborg A, Widder B (for the TESS Study Group). Teleneurology to Improve Stroke Care in Rural Areas - The Telemedicine in Stroke in Swabia (TESS) Project. Stroke 2003; 34: 2951-7.
externer Link

2000

Wiborg A, Widder B, Riepe MW, Krauß M, Huber R, Schmitz B. Beitrag der Telemedizin zur flächendeckenden Schlaganfallversorgung in ländlichen Gebieten. Akt Neurologie 2000; 27: 119–24.

Subnetz Klinische Schlaganfallstudien

2011

Siebler M, Hennerici MG, Schneider D, von Reutern GM, Seitz RJ, Röther J, Witte OW, Hamann G, Junghans U, Villringer A, Fiebach JB. Safety of Tirofiban in acute Ischemic Stroke: the SaTIS trial. Stroke. 2011 Sep;42(9):2388-92. Epub 2011 Aug 18.
externer Link

2010

Thomalla G, Hartmann F, Juettler E, Singer OC, Lehnhardt FG, Köhrmann M, Kersten JF, Krützelmann A, Humpich MC, Sobesky J, Gerloff C, Villringer A, Fiehler J, Neumann-Haefelin T, Schellinger PD, Röther J. Prediction of malignant middle cerebral artery infarction by magnetic resonance imaging within 6 hours of symptom onset: A prospective multicenter observational study. Ann Neurol. 2010 Oct;68(4):435-45.
externer Link

2008

Blondin D, Seitz RJ, Rusch O, Janssen H, Andersen K, Wittsack HJ, Turowski B. Clinical impact of MRI perfusion disturbances and normal diffusion in acute stroke patients. Eur J Radiol. 2008 May 17.
externer Link

Brosig T, Hoinkes A, Seitz RJ, Sandmann W, Huber R, Siebler M. Ultrasound turbulence index during thromboendarterectomy predicts postoperative cerebral microembolism. Cerebrovasc Dis. 2008;26(1):87-92.
externer Link

Dohmen C, Sakowitz OW, Fabricius M, Bosche B, Reithmeier T, Ernestus RI, Brinker G, Dreier JP, Woitzik J, Strong AJ, Graf R. Spreading depolarizations occur in human ischemic stroke with high incidence. Ann Neurol. 2008 Jun;63(6):720-8.
externer Link

Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, Skolnick BE, Steiner T; FAST Trial Investigators. Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2008 May 15;358(20):2127-37.
externer Link

Seitz RJ, Siebler M. Platelet GPIIb/IIIa receptor antagonists in human ischemic brain disease. Curr Vasc Pharmacol. 2008 Jan;6(1):29-36.
externer Link

Sengelhoff C, Nebelsieck J, Nassenstein I, Maintz D, Nabavi DG, Kuhlenbaeumer G, Ringelstein EB, Dittrich R. Neurosonographical follow-up in patients with spontaneous cervical artery dissection. Neurol Res. 2008 Sep;30(7):687-9.
externer Link

Steiner T, Jüttler E. American guidelines for the management of spontaneous intracerebral hemorrhage in adults: European perspective. Pol Arch Med Wewn. 2008 Apr;118(4):181-2.
externer Link

Steiner T, Walter-Sack I, Taupitz J, Hacke W, Strowitzki T. Ethische und juristische Aspekte beim Einschluss nicht einwilligungsfähiger Patienten in Akuttherapie-Studien. Beispiel einer Arzneimittelstudie zur Behandlung intrazerebraler Blutungen - das Heidelberger Verfahren. Dtsch med Wochenschr 2008; 133: 787-792.
externer Link

Veronel D, Ringelstein A, Cohnen M, Yong M, Siebler M, Seitz RJ. Systemic thrombolysis based on CT or MRI stroke imaging. J Neuroimaging. 2008 Oct;18(4):381-7.

2007

Dirks M, Niessen LW, Koudstaal J, Franke CL, van Oostenbrugge RJ, Dippel DW. Intravenous thrombolysis in acute ischaemic stroke: from trial exclusion criteria to clinical contraindications. An international Delphi study. J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):685-9.
externer Link

Dohmen C, Bosche B, Graf R, Reithmeier T, Ernestus RI, Brinker G, Sobesky J, Heiss WD. Identification and Clinical Impact of Impaired Cerebrovascular Autoregulation in Patients With Malignant Middle Cerebral Artery Infarction. Stroke 2007;38:56-61.
externer Link

Dreier JP, Kremer C, Lammers G, Lohmann F, Hansen HC, Valdueza JM. Migraine and delayed ischaemic neurological deficit after subarachnoid haemorrhage in women: a case-control study. Eur J Neurol. 2007 Dec;14(12):1363-8.
externer Link

Hacke W, Oertel W, Wick W, Hartung HP, Ringleb P, Diener HC. Die großen klinischen Studien – Evidenzbasierte Medizin in der Deutschen Neurologie. Akt Neurol 2007; 34: 386-9.
externer Link

Haeusler KG, Schmidt WU, Föhring F, Meisel C, Helms T, Jungehulsing GJ, Nolte CH, Schmolke K, Wegner B, Meisel A, Dirnagl U, Villringer A, Volk HD. Cellular immunodepression preceding infectious complications after acute ischemic stroke in humans. Cerebrovasc Dis. 2008;25(1-2):50-8. Epub 2007 Nov 22.
externer Link

Hohlfeld T, Weber AA, Junghans U, Schumacher M, Boucher M, Schror K, Siebler M; Variable Platelet Response to Aspirin in Patients with Ischemic Stroke. Cerebrovasc Dis 2007; 24(1): 43-50.
externer Link

Jüttler E, Schwab S, Schmiedek P, Unterberg A, Hennerici M, Woitzik J, Witte S, Jenetzky E, Hacke W. Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY): a randomized, controlled trial. Stroke. 2007 Sep;38(9):2518-25.
externer Link

Vahedi K, Hofmeijer J, Juettler E, Vicaut E, George B, Algra A, Amelink GJ, Schmiedeck P, Schwab S, Rothwell PM, Bousser MG, van der Worp HB, Hacke W. DECIMAL, DESTINY, and HAMLET investigators. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol. 2007;6(3):215-22.
externer Link

Weis-Müller BT, Huber R, Spivak-Dats A, Turowski B, Seitz R, Siebler M, Sandmann W. Indication for emergent revascularisation of acute carotid occlusion. Chirurg. 2007 Nov;78(11):1041-8.
externer Link

2006

Dreier JP, Woitzik J, Fabricius M, Bhatia R, Major S, Drenckhahn C, Lehmann T-N, Sarrafzadeh A, Willumsen L, Hartings JA, Sakowitz OW, Seemann JH, Thieme A, Lauritzen M, Strong AJ; Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarisations. Brain 2006; 129: 3224-37.
externer Link

Thomalla G, Schwark C, Sobesky J, Bluhmki E, Fiebach JB, Fiehler J, Zaro Weber O, Kucinski T, Juettler E, Ringleb PA, Zeumer H, Weiller C, Hacke W, Schellinger PD, Rother J. Outcome and symptomatic bleeding complications of intravenous thrombolysis within 6 hours in MRI-selected stroke patients: Comparison of a german multicenter study with the pooled data of atlantis, ecass, and ninds tPA trials. Stroke. 2006;37:852-858
externer Link

2005

Seitz RJ, Meisel S, Moll M, Wittsack HJ, Junghans U, Siebler M. Partial rescue of the perfusion deficit area by thrombolysis. J Magn Reson Imaging 2005; 22(2): 199-205.
externer Link

2004

Berger C, Dohmen C, Maurer M, Graf R, Schwab S. Zerebrale Mikrodialyse beim Schlaganfall. Nervenarzt 2004; 75(2): 113-23.
externer Link

Berger C, Schabitz WR, Wolf M, Mueller H, Sommer C, Schwab S. Hypothermia and brain-derived neurotrophic factor reduce glutamate synergistically in acute stroke. Exp Neurol 2004; 185: 305-12.
externer Link

Berger C, Schmid PC, Schabitz WR, Wolf M, Schwab S, Schmid HHO. Massive accumulation of N- acylethanolamines after stroke. Cell signaling in acute cerebral ischemia? J Neurochem 2004; 88(5): 1159-67.
externer Link

Bosche B, Dohmen C, Graf R. Cerebral Microdialysis in Stroke Patients: Potentials and Limitations of a Method with Longitudinal Information. Stroke 2004; DOI: 10.1161/01.STR.0000122627.37083.18, [Epub ahead of print].
externer Link

Schaller B, Graf R, Sanada Y, Wienhard K, Heiss WD. Decompressive hemicraniectomy in a new cat model. Methodologic description of the PET study protocol. Brain Res Protoc 2004; 12: 125-31.
externer Link

Straub S, Junghans U, Jovanovic V, Wittsack HJ, Seitz RJ, Siebler M. Systemic thrombolysis with recombinant tissue plasminogen activator and tirofiban in acute middle cerebral artery occlusion. Stroke 2004; 35: 705-9.
externer Link

2003

Berger C, Schwab S. “Malignant" or Not: Is There a Role for In Vivo Neurochemistry? Stroke 2003; 34: 2914-5.
externer Link

Bosche B, Dohmen C, Graf R, Neveling M, Staub F, Kracht L, Sobesky J, Lehnhardt FG, Heiss WD. Extracellular concentrations of non-transmitter amino acids in peri-infarct tissue of patients predict malignant middle cerebral artery infarction. Stroke 2003; 34(12): 2908-13.
externer Link

Dohmen C, Bosche B, Graf R, Staub F, Kracht L, Sobesky J, Neveling M, Brinker G, Heiss WD. Prediction of malignant course in MCA infarction by PET and microdialysis. Stroke 2003; 34(9): 2152-8.
externer Link

Heiss WD, Dohmen C, Sobesky J, Kracht L, Bosche B, Staub F, Toyota S, Valentino M, Graf R. Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis. Acta Neurochir Suppl 2003; 86: 237-40.
externer Link

Maurer MH, Berger C, Wolf M, Futterer CD, Feldmann, RE, Schwab S, Kuschinsky W. The proteome of human brain microdialysate. Proteome Sci 2003; 1(1): 7.
externer Link

Schaller B, Graf R, Sanada Y, Rosner G, Wienhard K, Heiss WD. Hemodynamic and metabolic effects of decompressive hemicraniectomy in normal brain. An experimental PET-study in cats. Brain Res 2003; 982(1): 31-7.
externer Link

Seitz RJ, Hamzavi M, Junghans U, Ringleb PA, Schranz C, Siebler M. Thrombolysis with recombinant tissue plasminogen activator and tirofiban in stroke: preliminary observations. Stroke 2003; 34:1932-5.
externer Link

Thomalla GJ, Kucinski T, Schoder V, Fiehler J, Knab R, Zeumer H, Weiller C, Rother J. Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging. Stroke 2003; 34: 1892-9.
externer Link

Toyota S, Graf R, Valentino M, Yoshimine T, Heiss WD. Prediction of malignant infarction: perifocal neurochemical monitoring following prolonged MCA occlusion in cats. Acta Neurochir Suppl 2003; 86: 153-7.
externer Link

2002

Junghans U, Seitz RJ, Ritzl A, Wittsack HJ, Fink GR, Freund HJ, Siebler M. Ischemic brain tissue salvaged from infarction by the GP IIb/IIIa platelet antagonist tirofiban. Neurology 2002; 58: 474-6.
externer Link

Subnetz Ultraschallforschung

2008

Stolz E, Cioli F, Allendoerfer J, Gerriets T, Del Sette M, Kaps M. Can early neurosonology predict outcome in acute stroke?: a metaanalysis of prognostic clinical effect sizes related to the vascular status. Stroke. 2008 Dec;39(12):3255-61.
externer Link

2007

Stolz E, Valdueza JM, Grebe M, Schlachetzki F, Schmitt E, Madlener K, Rahimi A, Kempkes-Matthes B, Blaes F, Gerriets T, Kaps M. Anemia as a risk factor for cerebral venous thrombosis? An old hypothesis revisited. Results of a prospective study. J Neurol 2007;254(6):729-34.
externer Link

Wunderlich MT, Goertler M, Postert T, Schmitt E, Seidel G, Gahn G, Samii C, Stolz E, for the Duplex Sonography in Acute Stroke (DIAS) Study Group and the Competence Network Stroke. Recanalisation after intravenous thrombolysis: Does a recanalisation time window exist? Neurology 2007; 68: 1364-8.
externer Link

2005

Wunderlich MT, Stolz E, Seidel G, Postert T, Gahn G, Sliwka U, Goertler M. Conservative Medical Treatment and Intravenous Thrombolysis in Acute Stroke from Carotid T Occlusion. Cerebrovasc Dis 2005; 2; 20(5): 355-61.
externer Link

2002

Gerriets T, Goertler M, Stolz E, Postert T, Sliwka U, Schlachetzki F, Seidel G, Weber S, Kaps M. Feasibility and validity of transcranial duplex sonography in acute stroke. J Neurol Neurosurg Psychiatry 2002; 73: 17-20.
externer Link

Subnetz Rehabilitation nach Schlaganfall

2009

Platz T, van Kaick S, Mehrholz J, Leidner O, Eickhof C, Pohl M. Best conventional therapy versus modular impairment-oriented training for arm paresis after stroke: a single-blind, multicenter randomized controlled trial. Neurorehabil Neural Repair. 2009 Sep;23(7):706-16.
externer Link

2008

Bütefisch CM, Wessling M, Netz J, Seitz RJ, Hömberg V. Relationship between interhemispheric inhibition and motor cortex excitability in subacute stroke patients. Neurorehabil Neural Repair. 2008 Jan-Feb;22(1):4-21.
externer Link

2007

Carey L M, Seitz RJ. Functional neuroimaging in stroke recovery and neurorehabilitation: conceptual issues and perspectives. Int J Stroke. 2007 Nov;2(4):245-64.
externer Link

Müller K, Bütefisch CM, Seitz RJ, Hömberg V. Mental practice improves hand function after hemiparetic stroke. Restor Neurol Neurosci. 2007;25(5-6):501-11.
externer Link

2006

Liepert J. Motor cortex excitability in stroke before and after Constraint-induced movement therapy. Cogn Behav Neurol 2006; 19(1):41-7.
externer Link

Seitz RJ, Bütefisch CM; Recovery from ischemic stroke: a translational research perspective for neurology. Future Neurol 2006; 1: 571-86.
externer Link

Siekierka-Kleiser E, Kleiser R, Wohlschläger AM, Freund H-J, Seitz RJ. Quantitative assessment of recovery from motor hemineglect in acute stroke patients. Cerebrovasc Dis 21: 307-314
externer Link

Weller P, Wittsack H-J, Siebler M, Hömberg V, Seitz RJ; Motor recovery as assessed with isometric finger movements and perfusion MRI after acute ischemic stroke. NNR 2006; 20: 390-97.
externer Link

2005

Bütefisch CM, Kleiser R, Körber B, Müller K, Wittsack H-J, Hömberg V, Seitz RJ. Recruitment of contralesional motor cortex in stroke patients with recovery of hand function. Neurology 64: 1067-1069
externer Link

Kleiser R, Wittsack H-J, Bütefisch CM, Jörgens S, Seitz RJ. Functional activation within the PI-DWI mismatch region in recovery from hemiparetic stroke: preliminary observations. Neuroimage 24: 515-523
externer Link

Liepert J, Restemeyer C, Kucinski T, Zittel S, Weiller C. Motor strokes: the lesion location determines motor excitability changes. Stroke. 2005; 36: 2648-53.
externer Link

Liepert J, Restemeyer C, Münchau A, Weiller C. Motor cortex excitability after thalamic infarction. Clin Neurophysiol. 2005; 116(7): 1621-7.
externer Link

Moliadze V, Giannikopoulos D, Eysel UT, Funke K. Paired-pulse transcranial magnetic stimulation protocol applied to visual cortex of anaesthetized cat: effects on visually evoked single-unit activity. J Physiol. 2005; 566(Pt 3): 955-65.
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Platz T, Eickhof C, van Kaick S, Engel U, Pinkowski C, Kalok S, Pause M. Impairment-oriented training or Bobath therapy for severe arm paresis after stroke: a single-blind, multicentre randomized controlled trial. Clin Rehabil 2005; 19(7): 714-24.
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Platz T, Kim IH, Engel U, Pinkowski C, Eickhof C, Kutzner M. Amphetamine fails to facilitate motor performance and to enhance motor recovery among stroke patients with mild arm paresis: interim analysis and termination of a double blind, randomised, placebo-controlled trial. Restor Neurol Neurosci. 2005; 23(5-6): 271-80.
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Platz T, Pinkowski C, van Wijck F, Kim I-H, di Bella P, Johnson G. Reliability and validity of arm function assessment with standardised guidelines for the Fugl-Meyer Test, Action Research Arm Test and Box and Block Test: a multi-centre study. Clin Rehabil 2005; 19(4): 404-11.
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Platz T, van Kaick S, Moller L, Freund S, Winter T, Kim IH. Impairment-oriented training and adaptive motor cortex reorganisation after stroke: a fTMS study. J Neurol. 2005;252 (11): 1363-71.
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Platz T. Apraxia - neuroscience and clinical aspects. A literature synthesis. Nervenarzt 2005; 76(10): 1209-10, 1213-4, 1216-8, 1220-1.
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Seitz RJ, Kleiser R, Bütefisch CM.Reorganization of cerebral circuits in human brain lesion. Acta Neurochir Suppl 93: 65-70
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Seitz RJ, Meisel S, Moll M, Wittsack H-J, Junghans U, Siebler M. Partial Rescue of the Perfusion Deficit Area by Thrombolysis. J Magnet Res Imaging 22: 199-205
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Seitz RJ, Meisel S, Weller P, Junghans U, Wittsack H-J, Siebler M.The initial ischemic event: PWI and ADC for stroke evolution. Radiology 237: 1020-1028
externer Link

2004

Binkofski F, Seitz RJ. Modulation of the BOLD-response in early recovery from sensorimotor stroke. Neurology 63: 1223-1229
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Butz M, Gross J, Timmermann L, Moll M, Freund HJ, Witte OW. Perilesional pathological oscillatory activity in the magnetoencephalogram of patients with cortical brain lesions. Neurosci Lett 2004; 355(1-2): 93-6.
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Elfeber K, Kohler A, Lutzenburg M, Osswald C, Galla HJ, Witte OW, Koepsell H. Localization of the Na(+)- d-glucose cotransporter SGLT1 in the blood-brain barrier. Histochem Cell Biol 2004; 121(3): 201-7.
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Fitzek S, Fitzek C, Huonker R, Reichenbach JR, Mentzel HJ, Witte OW, et al. Event-related fMRI with painful electrical stimulation of the trigeminal nerve. Magn Reson Imaging 2004; 22(2): 205-9.
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Kraemer M, Schormann T, Hagemann G, Bi Q, Witte OW, Seitz RJ. Delayed shrinkage of the brain after ischemic stroke: Preliminary Observations with Voxel-Guided Morphometry. J Neuroimaging 2004; 14(3): 265-72.
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Liepert J, Weiss T, Meissner W, Steinrucke K, Weiller C. Exercise-induced changes of motor excitability with and without sensory block. Brain Res 2004; 1003(1-2): 68-76.
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Ragert P, Becker M, Tegenthoff M, Pleger B, Dinse HR. Sustained increase of somatosensory cortex excitability by 5 Hz repetitive transcranial magnetic stimulation studied by paired median nerve stimulation in humans. Neurosci Lett 2004; 356: 91-4.
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Ritzl A, Meisel S, Wittsack H-J, Fink GR, Siebler M, Mödder U, Seitz RJ. Development of Brain Infarct Volume as assessed by Magnetic Resonance Imaging: Follow-up of DWI-lesions. J Magn Reson Imaging 2004; 20(2): 201-7.
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Seitz RJ, Bütefisch CM, Kleiser R, Hömberg V. Reorganization of cerebral circuits in human ischemic brain disease. Restor Neurol Neurosci 2004; 22(3-5): 207-29.
externer Link

Seitz RJ, Kleiser R, Bütefisch CM, Jörgens S, Neuhaus O, Hartung H-P, Wittsack H-J, Sturm V, Hermann MM. Bimanual recoupling by visual cueing in callosal disconnection. Neurocase 2004; 10: 316-325
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Seitz RJ, Meisel S, Moll M, Wittsack HJ, Junghans U, Siebler M. The Effect of Combined Thrombolysis with rtPA and Tirofiban on Ischemic Brain Lesions. Neurology 2004; 62(11): 2110-2.
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Stoeckel MC, Pollok B, Schnitzler A, Witte OW, Seitz RJ. Use-dependent cortical plasticity in thalidomide-induced upper extremity dysplasia: evidence from somaesthesia and neuroimaging. Exp Brain Res 2004; 156(3): 333-41.
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Straub S, Junghans U, Jovanovic V, Wittsack HJ, Seitz RJ, Siebler M. Systemic thrombolysis with recombinant tissue plasminogen activator and tirofiban in acute middle cerebral artery occlusion. Stroke 2004; 35: 705-9.
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Terborg C, Bramer S, Harscher S, Simon M, Witte OW. Bedside assessment of cerebral perfusion reductions in patients with acute ischaemic stroke by near-infrared spectroscopy and indocyanine green. J Neurol Neurosurg Psychiatry 2004; 75(1): 38-42.
externer Link

2003

Arckens L, Van der Gucht E, Van den Bergh G, Massie A, Leysen I, Vandenbussche E, Eysel UT, Huybrechts R, Vandesande F. Differential display implicates cyclophilin A in adult cortical plasticity. Europ J Neurosci 2003; 18: 61-75.
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Barmashenko G, Eysel UT, Mittmann T. Changes in intracellular calcium transients and LTP in the surround of visual cortex lesions in rats. Brain Research 2003; 990: 120-8.
externer Link

Bruehl C, Witte OW. Relation between bicarbonate concentration and voltage dependence of sodium currents in freshly isolated CA1 neurons of the rat. J Neurophysiol 2003; 89(5): 2489-98.
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Bütefisch CM, Netz J, Wessling M, Seitz RJ, Hömberg V. Remote changes in cortical excitability after stroke. Brain 2003; 126: 470-81.
externer Link

Dettmers C, Liepert J, Hamzei F, Binkofski F, Weiller C. Läsion im ventrolateralen prämotorischen Kortex beeinträchtigt die Greiffunktion. Akt Neurol 2003; 30: 247-55.

Diehm SM, Witte OW, Bruehl C. Differential alterations of the inactivation properties of high voltage activated calcium currents in area CA1 and CA3 of the rat following photothrombotic lesion. Neurosci Lett 2003; 341(2): 147-50.
externer Link

Gorsler A, Baumer T, Weiller C, Munchau A, Liepert J. Interhemispheric effects of high and low frequency rTMS in healthy humans. Clin Neurophysiol 2003; 114(10): 1800-7.
externer Link

Hagemann G, Kluska MM, Redecker C, Luhmann HJ, Witte OW. Distribution of glutamate receptor subunits in experimentally induced cortical malformations. Neuroscience 2003; 117(4): 991-1002.
externer Link

Hagemann G, Willig V, Fitzek C, Witte OW. Gunshot-induced artery dissection with twelfth nerve palsy. Arch Neurol 2003; 60(2): 280-1.
externer Link

Huber R, Muller BT, Seitz RJ, Siebler M, Modder U, Sandmann W. Carotid surgery in acute symptomatic patients. Eur J Vasc Endovasc Surg 2003; 25: 60-7.
externer Link

Janszky J, Ebner A, Kruse B, Mertens M, Jokeit H, Seitz RJ, et al. Functional organization of the brain with malformations of cortical development. Ann Neurol 2003; 53(6): 759-67.
externer Link

Liepert J, Gorsler A, van Eimeren T, Münchau A, Weiller C. Motor excitability in a patient with a somatosensory cortex lesion. Clin Neurophysiol 2003; 114: 1003-8.
externer Link

Liepert J, Weiller C. Recovery and plasticity imaging in stroke patients. In: Imaging in stroke (Hrsg. M. Hennerici) Remedica Publishing Ltd. London pp. 173-198. (2003)

Liepert J. Neue Therapien in der Neurorehabilitation. Akt Neurol 2003; 30: 209-14.

Liepert J. TMS in Stroke. Suppl Clin Neurophysiol 2003; 56: 368-80.
externer Link

Massie A, Cnops L, Jacobs S,Van Damme K, Vandenbussche E, Eysel UT, Vandesande F, Arckens L. Glutamate levels and transport in cat area 17 during cortical reorganization following binocular retinal lesions. J Neurochem 2003; 84: 1387-97.
externer Link

Massie A, Cnops L, Smolders I, Van Damme K, Vandenbussche E, Vandesande F, Eysel UT, Arckens L. Extracellular GABA concentrations in area 17 of cat visual cortex during topographic map reorganization following binocular central retinal lesioning. Brain Res 2003; 976: 100-8.
externer Link

Moliadze V, Zhao Y, Eysel UT, Funke K. Effect of transcranial magnetic stimulatioon on single-unit activity in the cat primary visual cortex. J Physiol 2003; 553: 665-79.
externer Link

Nickel J, Jokeit H, Wunderlich G, Ebner A, Witte OW, Seitz RJ. Gender-specific differences of hypometabolism in mTLE: implication for cognitive impairments. Epilepsia 2003; 44(12): 1551-61.
externer Link

Platz T. Evidenzbasierte Arm-Rehabilitation – eine systematische Literaturübersicht. Nervenarzt 2003; 74: 841-9.
externer Link

Qu Y, Massie A, van der Gucht E, Vandenbussche E, Eysel UT, Vandesande F, Arckens L. Retinal lesions affect extracellular glutamate levels in sensory-deprived and remote non-deprived regions of cat area 17 as revealed by in vivo microdialysis. Brain Res 2003; 962: 199-206.
externer Link

Reinecke S, Dinse HR, Reinke H, Witte OW. Induction of bilateral plasticity in sensory cortical maps by small unilateral cortical infarcts in rats. Eur J Neurosci 2003; 17(3): 623-7.
externer Link

Rossini PM, Liepert J. Lesion of cortex and post-stroke plastic reorganization. In “Plasticity in the Human Brain: Scientific and Clinical Studies with TMS" S Boniface &U Ziemann EDS (Cambridge University Press 2003) 166-203.

Seitz RJ, Hamzavi M, Junghans U, Ringleb PA, Schranz C, Siebler M. Thrombolysis With Recombinant Tissue Plasminogen Activator and Tirofiban in Stroke. Preliminary Observations. Stroke 2003; 34: 1932-5.
externer Link

Van den Bergh G, Eysel UT, Vandenbussche E, Vandesande F, Arckens L. Retinotopic map plasticity in adult cat visual cortex is accompanied by changes in Ca2+ / calmodulin-dependent protein kinase II alpha autophosphorylation. Neuroscience 2003; 120: 133-42.
externer Link

Weiss AC, Weiller C, Liepert J. Pre-movement motor excitability is reduced ipsilateral to low force pinch grips. J Neural Transm 2003; 110: 201-8.
externer Link

2002

Dihne M, Grommes C, Lutzenburg M, Witte OW, Block F. Different mechanisms of secondary neuronal damage in thalamic nuclei after focal cerebral ischemia in rats. Stroke 2002; 33(12): 3006-11.
externer Link

Eyding D, Schweigart G, Eysel UT. Spatio-temporal plasticity of cortical receptive fields in response to repetitive visual stimulation in the adult cat. Neuroscience 2002; 112: 195-215.
externer Link

Junghans U, Seitz RJ, Ritzl A, Wittsack HJ, Fink GR, Freund HJ, Siebler M. Ischemic brain tissue salvaged from infarction by the GP IIb/IIIa platelet antagonist tirofiban. Neurology 2002; 58: 474-6.
externer Link

Keyvani K, Witte OW, Paulus W. Gene expression profiling in perilesional and contralateral areas after ischemia in rat brain. J Cereb Blood Flow Metab 2002; 22(2): 153-60.
externer Link

Keyvani K, Witte OW, Reinecke S, Paulus W. Use-related gene expression patterns of rat motor cortex. Neuroreport 2002; 13(7): 953-6.
externer Link

Redecker C, Wang W, Fritschy JM, Witte OW. Widespread and long-lasting alterations in GABA(A)-receptor subtypes after focal cortical infarcts in rats: mediation by NMDA-dependent processes. J Cereb Blood Flow Metab 2002; 22(12): 1463-75.
externer Link

Schweigart G, Eysel UT. Activity-dependent receptive field changes in the surround of adult cat visual cortex lesions. Eur J Neurosci 2002; 15: 1585-96.
externer Link

Schwenkreis P, Tegenthoff M, Witscher K, Bornke C, Przuntek H, Malin JP, Schols L. Motorcortex activation by transcranial magnetic stimulation in ataxia patients depends on the genetic defect. Brain 2002; 125: 301-9.
externer Link

Stoeckel MC, Kleinschmidt A, Ebner A, Witte OW, Seitz RJ. Reorganization of motor representation in a patient with epilepsia partialis continua as shown by [O15]-labeled butanol positron emission tomography and functional magnetic resonance imaging. J Neuroimaging 2002; 12(3): 276-81.
externer Link

Terborg C, Birkner T, Schack B, Witte OW. Acute effects of cigarette smoking on cerebral oxygenation and hemodynamics: a combined study with near-infrared spectroscopy and transcranial Doppler sonography. J Neurol Sci 2002; 205(1): 71-5.
externer Link

Wittsack HJ, Ritzl A, Fink GR, Wenserski F, Siebler M, Seitz RJ, Modder U, Freund HJ. MR Imaging in Acute Stroke: Diffusion-weighted and Perfusion Imaging Parameters for Predicting Infarct Size. Radiology 2002; 222: 397-403.
externer Link

Subnetz Public Health

2010

P. U. Heuschmann, O. Busse, M. Wagner, M. Endres, A. Villringer, J. Röther, P. L. Kolominsky-Rabas, K. Berger. Schlaganfallhäufigkeit und Versorgung von Schlaganfallpatienten in Deutschland. Akt Neurol 2010; 37(7): 333-340.DOI: 10.1055/s-0030-1248611.
externer Link

2009

Müller-Nordhorn J, Wegscheider K, Nolte CH, Jungehülsing GJ, Rossnagel K, Reich A, Roll S, Villringer A, Willich SN. Population-based intervention to reduce prehospital delays in patients with cerebrovascular events. Arch Intern Med. 2009 Sep 14;169(16):1484-90.
externer Link

Nolte CH, Jungehulsing GJ, Rossnagel K, Roll S, Haeusler KG, Reich A, Willich SN, Villringer A, Muller-Nordhorn J. Vascular risk factor awareness before and pharmacological treatment before and after stroke and TIA. Eur J Neurol. 2009 Jun;16(6):678-83.
externer Link

2008

Jungehülsing GJ, Müller-Nordhorn J, Nolte CH, Roll S, Rossnagel K, Reich A, Wagner A, Einhäupl KM, Willich SN, Villringer A. Prevalence of stroke and stroke symptoms: a population-based survey of 28,090 participants. Neuroepidemiology. 2008;30(1):51-7.
externer Link

2007

Brüggenjürgen B, Rossnagel K, Roll S, Andersson FL, Selim D, Müller-Nordhorn J, Nolte CH, Jungehülsing G J, Villringer A, Willich S N. The impact of atrial fibrillation on the cost of stroke: the berlin acute stroke study. Value Health 2007; VOL 10 (2): 137–43.
externer Link

Kraywinkel K, Heidrich J, Heuschmann PU, Wagner M, Berger K. Stroke risk perception among participants of a stroke awareness campaign. BMC Public Health 2007; 7:39.
externer Link

2006

Heuschmann PU, Berger K. International experience in stroke registries: German Stroke Registers Study Group. Am J Prev Med. 2006; 31:238-9.
externer Link

Heuschmann PU, Biegler MK, Busse O, Elsner S, Grau A, Hasenbein U, Hermanek P, Janzen RW, Kolominsky-Rabas PL, Kraywinkel K, Lowitzsch K, Misselwitz B, Nabavi DG, Otten K, Pientka L, von Reutern GM, Ringelstein EB, Sander D, Wagner M, Berger K. Development and implementation of evidence-based indicators for measuring quality of acute stroke care: the Quality Indicator Board of the German Stroke Registers Study Group (ADSR). Stroke 2006; 37: 2573-8
externer Link

Heuschmann PU, Biegler MK, Busse O, Elsner S, Grau A, Hasenbein U, Hermanek P, Janzen RW, Kolominisky-Rabas PL, Kraywinkel K, Lowitzsch K, Misselwitz B, Nabavi DG, Otten K, Pientka L, von Reutern GM, Ringelstein EB, Sander D, Wagner M, Berger K. Development and Implementation of Evidence-Based Indicators for Measuring Quality of Acute Stroke Care. Stroke. 2006; 37(10): 2573-8.
externer Link

Jungehülsing GJ, Rossnagel K, Nolte CH, Müller-Nordhorn J, Roll S, Klein M, Wegscheider K, Einhäupl KM, Willich SN, Villringer A. Emergency department delays in acute stroke – analysis of time between ED arrival and imaging. Eur J Neurol. 2006; 13(3): 225-32.
externer Link

Kolominsky-Rabas PL, Heuschmann PU, Marschall D, Emmert M, Baltzer N, Neundörfer B, Schöffski O, Krobot KJ, for the CompetenceNet Stroke. Lifetime Cost of Ischemic Stroke in Germany. Results and National Projections from a Population-Based Stroke Registry: the Erlangen Stroke Project. Stroke 2006; 37(5): 1179-83.
externer Link

Müller-Nordhorn J, Nolte CH, Rossnagel K, Jungehulsing GJ, Reich A, Roll S, Villringer A, Willich SN. Medical management in patients following stroke and transitory ischemic attack: a comparison between men and women. Cerebrovasc Dis. 2006; 21(5-6): 329-35.
externer Link

Müller-Nordhorn J, Nolte CH, Rossnagel K, Jungehülsing GJ, Reich A, Roll S, Villringer A, Willich SN. Knowledge about risk factors for stroke: a population-based survey with 28,090 participants. Stroke 2006; 37(4): 946-50.
externer Link

Nolte CH, Muller-Nordhorn J, Jungehulsing GJ, Rossnagel K, Reich A, Roll S, Laumeier I, Beerfelde D, Willich SN, Villringer A. Two simple questions to diagnose post-stroke depression. Fortschr Neurol Psychiatr. 2006; 74(5): 251-6.
externer Link

Wagner M, Roebers S, Breckenkamp J, Heidrich J, Mohn B, Berger K, Heuschmann P. Veränderungen in der Wahrnehmung der Risikofaktoren für einen Schlaganfall in der deutschen Bevölkerung zwischen 1995/ 1996 und 2000/ 2001. Dtsch Med Wochenschr 2006; 131: 314-318.
externer Link

Weimar C, Goertler M, Harms L, Diener HC. Distribution and Outcome of Symptomatic Stenoses and Occlusions in Patients with Acute Cerebral Ischemia. Arch Neurol 2006; 63: 1287-1291.
externer Link

Weimar C, Ho TW, Katsarava Z, Diener HC. Improving Patient Selection for Clinical Acute Stroke Trials. Cerebrovasc Dis 2006; 21(5-6): 386-392.
externer Link

Weimar C, Kraywinkel K, Maschke M, Diener HC; Intravenous thrombolysis in German Stroke Units before and after regulatory approval of recombinant tissue plasminogen activator (rtPA). Cerebrovasc Dis 2006; 22:429-31.
externer Link

Weimar C, Roth M, Willig V, Kostopoulos P, Benemann J, Diener HC; for the German Stroke Study Collaboration. Development and validation of a prognostic model to predict recovery following intracerebral hemorrhage. J Neurol 2006; DOI: 10.1007/s00415-006-0119-x, [Epub ahead of print].
externer Link

2005

Heuschmann PU, Kolominsky-Rabas PL, Nolte CH, Hunermund G, Ruf HU, Laumeier I, Meyrer R, Alberti T, Rahmann A, Kurth T, Berger K. Untersuchung der Reliabilität der deutschen Version des Barthel-Index sowie Entwicklung einer postalischen und telefonischen Fassung für den Einsatz bei Schlaganfall-Patienten. Fortschr Neurol Psychiatr. 2005; 73(2): 74-82.
externer Link

Kraywinkel K, Görtler M, Haass AH, Weimar C; for the German Stroke Study Collaboration.Diagnostic Benefit of Transesophageal Echocardiography after TIA and Ischemic Stroke. Akt Neurol 2005, 32: 129-135.

Müller-Nordhorn J, Nolte CH, Rossnagel K, Jungehülsing GJ, Reich A, Roll S, Villringer A, Willich SN. The use of the 12-item short-form health status instrument in a longitudinal study of patients with stroke and transient ischaemic attack. Neuroepidemiology 2005; 24(4): 196-202.
externer Link

Nolte CH, Muller-Nordhorn J, Jungehulsing GJ, Rossnagel K, Reich A, Klein M, Willich SN, Villringer A. Symptome, Risikofaktoren und Ätiologie von transitorisch ischämischer Attacke und Schlaganfall. Nervenarzt. 2005; 76(10): 1231-8.
externer Link

Nolte CH, Rossnagel K, Jungehuelsing GJ, Muller-Nordhorn J, Roll S, Reich A, Willich SN, Villringer A; German Competence Net Stroke. Gender differences in knowledge of stroke in patients with atrial fibrillation. Prev Med. 2005; 41(1): 226-31.
externer Link

Nolte CH, Villringer A. Outpatient and prehospital care of patients with risk factors for a stroke and of patients with acute stroke – results from the Competence Network Stroke. Med Welt 2005; 56: 79-82.

Rossnagel K, Nolte CH, Muller-Nordhorn J, Jungehulsing GJ, Selim D, Bruggenjurgen B, Villringer A, Willich SN. Medical resource use and costs of health care after acute stroke in Germany. Eur J Neurol. 2005; 12(11): 862-8.
externer Link

Ward A, Payne KA, Caro JJ, Heuschmann PU, Kolominsky-Rabas PL. Care needs and economic consequences after acute ischemic stroke: the Erlangen Stroke Project. Eur J Neurol. 2005; 12(4): 264-7.
externer Link

Weimar C, Benemann J, Diener HC. Development and validation of the Essen intracerebral hemorrhage score. J Neurol Neurosurg Psychiatry 2005; DOI:10.1136/jnnp.2005.081117.
externer Link

Weimar C, Mieck T, Buchthal J, Ehrenfeld CE, Schmid E, Diener HC; German Stroke Study Collaboration. Neurologic worsening during the acute phase of ischemic stroke. Arch Neurol 2005; 62(3): 393-7.
externer Link

2004

Heuschmann PU, Kolominsky-Rabas PL, Misselwitz B, Hermanek P, Leffmann C, Janzen RWC, Rother J, Buecker-Nott HJ, Berger K; German Stroke Registers Study Group. Predictors of In-Hospital-Mortality and Attributable Risks of Death after Ischemic Stroke. Arch Intern Med 2004; 164(16): 1761-8.
externer Link

Heuschmann PU, Kolominsky-Rabas PL, Misselwitz B, Hermanek P, Leffmann C, von Reutern GM, Lachenmayer L, Buecker-Nott HJ, Berger K. Einflussfaktoren auf die stationäre Liegezeit nach Schlaganfall in Deutschland. Die Arbeitsgemeinschaft Deutscher Schlaganfallregister (ADSR). Dtsch Med Wochenschr 2004; 129(7): 299-304.
externer Link

Heuschmann PU, Kolominsky-Rabas PL, Rother J, Misselwitz B, Lowitzsch K, Heidrich J, Hermanek P, Leffmann C, Sitzer M, Biegler M, Buecker-Nott HJ, Berger K; German Stroke Registers Study Group. Predictors of in-hospital mortality in patients with acute ischemic stroke treated with thrombolytic therapy. JAMA 2004; 292(15): 1831-8.
externer Link

Rossnagel K, Jungehulsing GJ, Nolte CH, Muller-Nordhorn J, Roll S, Wegscheider K, Villringer A, Willich SN. Out-of-hospital delays in patients with acute stroke. Ann Emerg Med. 2004; 44(5): 476-83.
externer Link

2003

Heuschmann PU, Berger K, Misselwitz B, Hermanek P, Leffmann C, Adelmann M, Buecker-Nott HJ, Rother J, Neuendoerfer B, Kolominsky-Rabas PL; German Stroke Registers Study Group; Competence Net Stroke. Frequency of thrombolytic therapy in patients with acute ischemic stroke and the risk of in-hospital-mortality: the German Stroke Registers Study Group. Stroke 2003; 34(5): 1106-13.
externer Link

Jahn H, Hetzel A, Luckner A, Niebling W. Entwicklung von Qualitätsindikatoren (QIs) zur Evaluation hausärztlicher Sekundärprävention nach Schlaganfall. Z Allg Med 2003; 79: 2-38.

Kolominsky-Rabas PL, Hilz MJ, Neundoerfer B, Heuschmann PU. Impact of urinary incontinence after stroke: Results from a prospective population-based stroke register. Neurourology and Urodynamics 2003; 22: 322-7.
externer Link

Kompetenznetz

2010

P. U. Heuschmann, O. Busse, M. Wagner, M. Endres, A. Villringer, J. Röther, P. L. Kolominsky-Rabas, K. Berger. Schlaganfallhäufigkeit und Versorgung von Schlaganfallpatienten in Deutschland. Akt Neurol 2010; 37(7): 333-340.DOI: 10.1055/s-0030-1248611.

2009

Audebert H.J., Berger K., Boy S., Einhäupl K.M., Endres M., Gahn G., Handschu R., Kaps M., Kuschinsky W., Lichy C., Röther J., Schenkel J., Scibor M., Schleyer A., Siebler M., Witte O.W., Ziegler V., Villringer A. Telemedizin in der akuten Schlaganfallversorgung - Review und Empfehlungen des Kompetenznetzes Schlaganfall. Akt Neurol 2009; 36: 82-90.
externer Link

Thomalla G., Audebert H.J., Berger K., Fiebach J.B., Fiehler J., Kaps M., Neumann-Haefelin T., Schellinger P.D., Siebler M., Sobesky J., Villringer A., Witte O.W., Röther J. Bildgebung beim Schlaganfall - eine Übersicht und Empfehlungen des Kompetenznetzes Schlaganfall. Akt Neurol 2009; 36: 354-367.
externer Link

2007

Jungehülsing GJ, Brunecker P, Nolte CH, Fiebach JB, Kunze C, Doepp F, Villringer A, Schreiber SJ.Diagnostic transcranial ultrasound perfusion-imaging at 2.5 MHz does not affect the blood-brain barrier. Ultrasound Med Biol 2008; 34(1):147-50; [Epub 2007, ahead of print].
externer Link

2006

Nolte CH, Clevert L, Villringer A; Vernetzt forschen – schneller umsetzen - Zum Wohle des Patienten – Kompetenznetz Schlaganfall. Nervenheilkunde 2006; 25 (11): 899-900.
externer Link

Nolte CH, Jungehülsing GJ, Muller-Nordhorn J, Rossnagel K, Roll S, Willich SN, Villringer A; Die Berliner Akuter Schlaganfall Studie - Schwachstellen und Verbesserungsmöglichkeiten in der Versorgung von Patienten mit akutem Schlaganfall. Nervenheilkunde 2006; 25 (11): 901-5.
externer Link

Nolte CH, Villringer A; Kompetenznetz Schlaganfall. The German competence network stroke: researching -- promoting -- networking. Med Klin (Munich) 2006; 101(3): 250-4. German
externer Link

Platz T, Liepert J, Seitz RJ, Bütefisch CM, Müller K, Suchan B, Hömberg V, Weiller C, Witte O; Erholung im motorischen System nach Hirnschädigung. Nervenheilkunde 2006; 25 (11): 933-40.
externer Link

S Külkens, P Ringleb, J Diedler, W Hacke,T Steiner; Empfehlungen der European Stroke Initiative für Diagnose und Behandlung spontaner intrazerebraler Blutungen. Der Nervenarzt. 2006;77:970-88.
externer Link

Siebler M, Laufen A; Können uns Decison Support Systeme in der akuten Schlaganfalltherapie helfen? Nervenheilkunde 2006; 25 (11): 906-10.
externer Link

Steiner T, Rosand J, Diringer M; Intracerebral Hemorrhage Associated with Oral Anticoagulant Therapy: Current Practices and Unresolved Questions. Stroke 2006; 37:256-62
externer Link

Steiner T, Schneider D, Mayer S, Begtrup K, Broderick J,Schneider D,Skolnick B, Davis S; Dynamics of intraventricular Hemorrhage in Patients with spontaneous intracerebral Hemorrhage: Risk Factors, Clinical Impact, and Effect of Hemostatic Theraphie with Recombinant Activated Factor VII. Neurosurgery. 2006;59:767-74
externer Link

Steiner T; Iatrogene intrakranielle Blutungen. Eine reale Gefahr. Aktuelle Neurologie 2006; Sonderband: 789-94.
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